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Dr. Curtis - What the Science says about Fungus

Pulmonary aspergillosis: a clinical update
Aspergillus spp may cause a variety of pulmonary diseases, depending on immune status and the presence of underlying lung disease. These mani- festations range from invasive pulmonary aspergil- losis in severely immunocompromised patients, to chronic necrotizing aspergillosis in patients with chronic lung disease and/or mildly compromised immune sy...

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Endogenous ethanol production in a patient with chronic intestinal pseudo-obstruction and small intestinal bacterial overgrowth
The case of the gastrointestinal production of ethanol from Candida albicans and Saccharomyces cerevisiae in a Caucasian man with chronic intestinal pseudo-obstruction is reported. The patient, who declared to have always abstained from alcohol, was hospitalized for abdominal pain, belching and mental confusion. The laboratory findings showed the p...

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Diagnosis and Incidence of Allergic Fungal Sinusitis
Diagnosis and Incidence of Allergic Fungal Sinusitis


The Role of Ubiquitous Airborne Fungi in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a confusing disease for both allergists and otorhino- laryngologists, partly because of its poorly understood pathophysiology and partly because of its limited treatment options. Several recent reports have provided evidence for a better under- standing of the etiology and the relationship of CRS to airborne fungi—es...

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Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans
Ochratoxin A (OTA) is a ubiquitous mycotoxin produced by fungi of improperly stored food pro- ducts. OTA is nephrotoxic and is suspected of being the main etiological agent responsible for human Balkan endemic nephropathy (BEN) and associated urinary tract tumours. Striking similarities between OTA-induced porcine nephropathy in pigs and BEN in hum...

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Epidemiology of Invasive Mycoses in North America
The incidence of invasive mycoses is increasing, especially among patients who are immunocompromised or hospitalized with serious underlying diseases. Such infections may be broken into two broad categories: opportunistic and endemic. The most important agents of the opportunistic mycoses are Candida spp., Cryptococcus neoformans, Pneumocystis jiro...

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